It is no use doing sth与It is no use to do sth的区别为：含义不同、用法不同。

1.含义不同It is no use doing sth翻译：做某事是没有用的It is no use to do sth翻译：做某事没用。

2.用法不同It is no use doing sth用法：这是固定搭配，doing sth是肯定的，绝对没错。It is no use to do sth用法：to do sth，是用在be used to do sth被用来做某事。拓展不定式的一般式表示事实性、经常性或一般性动作或情况，而不定式的进行式表示正在进行的动作。例如：He pretended to be doing his homework when I came in.我进来时他假装正在看书。I don't pretend to know as much as he does about it. 我不敢说我对此事的了解有他那样多.